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系所資訊
吳東信 教授

吳東信 Tung-Hsin Wu 教授

生物醫學影像暨放射科學系
Department of Biomedical Imaging and Radiological Sciences

 
 

實驗室網站:

中文版:國立陽明大學 醫學影像整合實驗室

英文版:National Yang-Ming University Medical Imaging Integration Lab

 

研究領域:

醫學影像整合與應用、核醫與分子影像、電腦斷層、放射治療與輻射劑量

研究領域-吳東信 教授


聯絡資訊:

研究室:研究大樓112室 02-2826-7061

e-mail:tung@ym.edu.tw


工作經歷:

2013-至今 國立陽明大學 生醫影像暨放射科學系 專任教授

2009-2013 國立陽明大學 生醫影像暨放射科學系 專任副教授

2007-2009 中山醫學大學 醫學影像暨放射科學系 專任副教授

2004-2007 中山醫學大學 醫學影像暨放射科學系 專任助理教授

 

學歷:

國立清華大學生醫工程與環境科學系 博士


證書:

輻射防護師證書 輻專師字第01073號

 



國立陽明大學 醫學影像整合實驗室

National Yang-Ming University Medical Imaging Integration Lab.

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你們知道將醫學影像設備應用在心血管攝影(cardiovascular imaging)有著全球最熱門的議題嗎?心臟的跳動與結構是個極為複雜的器官,心跳週期和呼吸週期相差甚大,控制影像品質的因素眾多,病人所需接受的輻射劑量(radiation dose)又和影像品質(image quality)與臨床需求息息相關,因此,如何建立輻射劑量最小化、影像品質最佳化,任何造影的應用就可以更上一層樓,是不是讓人熱血沸騰?前所未有的影像整合實驗正等著我們!

醫學影像整合對於疾病的診斷與治療絕對是日趨重要,本研究團隊除探討心血管攝影的影像整合外,許多的影像技術經過改良後都能連結於核醫影像(PET/SPECT/CT)及放射治療(radiation therapy)的整合中,是否讓你更加好奇醫學影像整合的魔力呢?


 

實驗室成員


吉祥物 --- 咪寶 (Miibo)

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博士班研究生(入學年度):

  1. 蔡瑞鵬 - 臺北馬偕醫院 心臟內科暨加護病房(100)
  2. 孫靜儀 - 慈濟技術學院 醫放系畢業(100)
  3. 吳念芸 - 台北榮總 核醫部(101)
  4. 杜俊元 - 臺北馬偕醫院 放射診斷科(103)
  5. 蔡維達 - 大林慈濟醫院 放射腫瘤科&一學物理中心(103)
  6. 丁雲龍 - 和信治癌中心醫院 放射診斷科(103)
  7. 汪姍瑩 - 亞東紀念醫院 核子醫學科(103)
  8. 徐晨雄 - 亞東紀念醫院 放射腫瘤科(104)
  9. 陳冠名 - 中山醫學大學醫放系畢業 (105)
  10. 林冠亨 - 中山醫學大學醫放系畢業 (105)
  11. 許志全 - 愛心動物醫院 (105)
     

碩士班研究生(入學年度):

  1. 蔡沛宜 – 中山醫學大學醫放系畢業 (104)
  2. 賴冠任 – 中山醫學大學醫放系畢業 (105)
  3. 陳昱睿 – 陽明大學醫放系畢業 (105)
  4. 鄧福根 – 人人動物醫院 (105)
     

實驗室畢業生(現職):

  1. 蔡佳容 - 中山醫藥大學 醫學影像暨放射科學系 助理教授
  2. 李詠馨 - 財政部關務署 (關務人員考試通過)
  3. 于志安 - 財政部關務署 (關務人員考試通過)
  4. 林詩航 - 財政部關務署 (關務人員考試通過)
  5. 陳彥綸 - 替代役(海巡署)
  6. 鄭敬瀚 - 研發替代役 (核研所 保健物理組)
  7. 蔡馨儀 - 陽明醫院放射科
  8. 官郁翔 - 台北市立聯合醫院 仁愛院區 核醫部
  9. 陳韋新 - 財政部關務署 (關務人員考試通過)
  10. 林仰賢 - 台灣大學(博士班)
  11. 張秋涵 - 亞東醫院 放射治療科
  12. 蔡孟芬 - 高雄榮民總醫院 放射診斷部
  13. 李易濰 - 高雄長庚紀念醫院 放射診斷科
  14. 林士軒 - 替代役(醫療役)
  15. 惲純和 - 臺北馬偕醫院 放射診斷科
  16. 陳冠伶 - 中港澄清醫院 放射腫瘤科
  17. 胡紹均 - 替代役(醫療役)
     

國內外合作夥伴:

  1. 台北榮民總醫院
  2. 新光吳火獅紀念醫院
  3. 台北馬偕醫院
  4. 亞東紀念醫院
  5. 中華醫事放射全國聯合會
  6. 澳門大學
  7. 美國克里夫蘭凱斯大學

研究領域簡介

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1.醫學影像成像原理與應用:每種造影設備,都具有它存在的特殊價值,因此,整合多種影像設備(如MRI, CT, PET, SPECT等),增加診斷資訊,以提高臨床的應用性,這樣的整合問題,就變成是一個很有趣的研究主題。如本研究團隊將4D-CT配合呼吸門控(Respiratory-gated)應用在降低呼吸運動可能導致的PET/CT肺部錯誤診斷,由於胸、腹腔器官會隨著呼吸而有週期性運動,最大的位移量可達2公分,因CT掃描速度快,所得到的CT影像在執行PET衰減校正時(attenuation correction),會因週期移動的關係在胸腔及心臟攝影時出現影像錯位(image misalignment)的現象,進而影響診斷結果,為了解決此問題,我們使用形變影像對位(B-spline algorithm)改進cine CT技術進而提出內插平均CT (interpolated average CT, IACT)的概念(如下圖),使用此IACT影像執行衰減校正所獲得的影像進行診斷或評估胸腹腔的腫瘤時,可順利解決大多數影像錯準的問題,也可以使衰減校正所需接受的輻射劑量降至為0.38 mSv。IACT技術執行成功的先決條件為病人需要維持穩定的呼吸週期,因此,我們需進一步使用精準度高的主動式呼吸調控系統(active breath control system, ABC)對病人進行呼吸調控,本人目前和澳門大學-電機電子工程系進行合作,自行研發出一套主動式呼吸調控內插平均CT系統IACT-ABC,並自行撰寫程式來調控此系統,目前自製之IACT-ABC原型機已研發完成,這樣的原型更是全球首例,現已完成若干相關的臨床測試。

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2.電腦斷層:近年來,多排偵檢器電腦斷層 (multi detector computer tomography, MDCT)對於心血管疾病的診斷有著快速的發展,不僅提供無侵入性的優勢外,更可整合時間資訊,提供動態之四維電腦斷層掃描(four-dimensional computed tomography, 4D-CT),提高診斷價值。近年我們的研究發現對於CT冠脈血管攝影而言,心率的快慢以及變化率對影像的影響遠大於呼吸運動的影響。除此之外,CT冠脈血管攝影帶給病患高輻射劑量一直是眾所關注的議題。這一系列的4D-CT研究我們除了用在一般CT冠脈血管攝影外,也應用在心房纖維性顫動(atrial fibrillation)、320切CT冠脈血管攝影及PET/CT的心臟檢查等。近期本人與指導的博士班團隊更將研究領域擴及到電腦斷層於冠脈繞道(Coronary Artery Bypass Graft, CABG)的術後檢查、小兒先天性心臟病、心臟鈣化分析、局部特定脂肪與心血管疾病因子之相關性、及電腦斷層導引導管射頻燒灼(catheter ablation)之相關研究。團隊這些年來與美國克里夫蘭凱斯大學醫學中心心血管影像核心實驗室已建立良好的合作關係,經由台北馬偕的連結,雙方一同探討左心室血管瘤於治療前與治療後心臟功能的變化,本團隊則負責利用電腦斷層評估心室分區裝置(ventricular partitioning device)於心室重建的治療機制,這些初步的研究成果都獲得相當好的評價。

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3.核醫與分子影像:正子攝影(PET)的功能性造影(functional imaging)與分子影像(molecular imaging)一直都是生物醫學最熱門的研究主題之一,關於核醫的腦功能影像分析,過去研究團隊也有很好的表現,珠心算技能是中華文化獨一無二的特色,我們曾經使用O15-H2O的PET影像,進行一般人與珠心算高手在進行不同難度運算時的腦部功能性影像分析,藉此了解表現在處理數學運算時所使用的神經途徑探討。團隊也將過去PET腦功能影像分析的經驗,應用在建置Tc-99m TRODAT-1自動化定量分析平台。小動物分子影像方面,曾利用MRI與microPET影像整合與立體定位技術,設計一套小鼠的立體定位穿刺系統,也使用蒙地卡羅技術模擬小動物模型,探討造影時間、放射性追蹤劑的活性(radioactivity)、最佳腫瘤偵測效應及衰減校正(attenuation correction)等研究。

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4.輻射劑量量測:提供高品質影像診斷與放射治療的背後,輻射量測(radiation measurement)一直扮演著重要的角色,影像品質、治療計畫、臨床可行性與劑量評估間的關係,就成了我最有興趣的研究主題之一。呼吸運動導致影像錯準的問題不僅可能導致PET/CT的診斷錯誤,此問題更存在於放射治療中,病人在治療過程中處於正常呼吸,如何才能精準的配合呼吸週期將劑量集中於腫瘤,大幅減少周圍正常組織所需接受的劑量,這都是一些相當具有挑戰的題目。為了確定我們所設定的治療劑量和機器輸出劑量一致,過去我們擁有使用MAGAT三維劑量膠進行劑量量測,並搭配使用MRI計讀,MAGAT相較於Fricke等其他化學劑量計,有易備製,準確度較高等優點,配合這樣的相關技術或許未來也可應用在重粒子(質子)治療的相關研究。

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5.心功能流體力學模擬:隨著放射醫學與數位科技的進步,利用CT,MRI或其他高解析度三維立體影像來研究血流動力學將會是心血管疾病的熱門研究,也是現今醫療科技的趨勢。電腦計算流體力學模擬(Computational Fluid Dynamics Simulation)可以提供非侵入式的各種動態、直觀的血管功能性檢查,幫助臨床了解疾病發生和預後手術治療的血流變化,這是本研究團隊目前較具嘗試性的研究題目。

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研究計畫



1. 國科會94年專題研究計畫-主持人
運算中的大腦神經機轉:利用功能性磁振影像研究珠心算高手與一般人的比較
計畫編號:NSC 94-2314-B-040-025
執行期限:94/08/01~95/07/31. 

2. 國科會95年專題研究計畫-主持人
發展小動物影像導引定位系統:結合分子造影與高品質解剖影像
計畫編號:NSC 95-2314-B-040-024
執行期限:95/08/01~96/07/31. 

3. 國科會95年專題研究計畫-主持人
整合多模式影像資訊於螺旋式斷層治療
計畫編號:NSC 95-2314-B-040 -023
執行期限:95/08/01~96/10/31. 

4. 國科會95年大專學生參與國科會計畫-指導教授
用逐像素形態分析法探討阿茲海默症患者腦部萎縮程度與短期記憶能力之相關性
計畫編號:NSC 95-2815-C-040-026-B
執行期限:95/07/01~96/02/28.; 學生姓名:吳奕螢

5. 國科會96-98年專題研究計畫(新制三年期)-主持人
新型錐形射束電腦斷層血管攝影之性能評估與影像改善
計畫編號:NSC96-2321-B-040-005-MY3
執行期限:96/08/01~99/7/31. 

6. 國科會97年大專學生參與國科會計畫-指導教授
低劑量內插平均CT降低PET/CT呼吸假影的可行性研究
計畫編號:NSC 97-2815-C-040-027-B
執行期限:97/07/01~98/02/28.; 學生姓名:吳念芸

7. 國科會97年大專學生參與國科會計畫-指導教授
MAGAT多體劑量膠於近接治療的三度空間劑量分佈評估
計畫編號:NSC 97-2815-C-040-027-B
執行期限:97/07/01~98/02/28.; 學生姓名:劉映汝

8. 國科會97-98年專題研究計畫(新制二年期)-共同主持人
利用高靈敏度多體劑量膠評估其三維劑量分佈於影像導航與呼吸閘道調控放射治療之研究
計畫編號:97-2314-B-010-044-MY2
執行期限:97/08/01~99/7/31. 

9. 考選部99年公務人員特種考試關務人員考試三等考試輻射安全技術工程科別應試科目命題大綱委託研究案-協同主持人
執行期限:99/04/01~99/9/30.

10.國科會99-102年專題研究計畫(新制三年期)-主持人
結合雙能量與低劑量特性的CT造影於PET衰減校正的應用
計畫編號:NSC99-2314-B-010-043-MY3
執行期限:99/08/01~102/7/31.

11.國科會100年專題研究計畫-共同主持人
以數位減影X光血管攝影定量分析顱內血管性疾病的相關血流動力學
計畫編號:NSC 100-2314-B-075-022
執行期限:100/08/01~101/07/31.

12.台灣電力股份有限公司委託研究計畫-共同主持人
極低頻電磁場暴露健康風險評估與溝通策略之研究
計畫編號:101J002
執行期限:100/11/01~101/10/31.

13.國科會101年原子能合作研究計畫(個別型)-主持人
建置Tc-99m TRODAT-1自動化定量分析平台
計畫編號:NSC 101-2623-E-010 -003 -NU
執行期限:101/01/01~101/12/31.

14.國科會101年一般型研究計畫(個別型) ─ 主持人
發展低劑量雙能數位式乳房攝影技術於提升微鈣化組織之偵測研究
計畫編號:NSC 101-2314-B-010-047-MY2
執行期限:101/08/01~103/07/31

15.衛生福利部委託研究計畫-主持人
醫用電腦斷層掃瞄儀輻射暴露品質指標確保計畫
計畫編號:M03A2025
執行期限:103/01/01~103/12/20

16.國科會103年一般型研究計畫(個別型)-主持人
發展左心房三維型態地圖導引及量化法於心血管疾病診斷及電腦斷層導引導管射頻燒灼
計畫編號:103-2314-B-010-005-MY3
執行期限:103/08/01~106/07/31

17.國科會103年一般型研究計畫(個別型)-共同主持人
心臟電腦斷層評估心室分區裝置於心室重建的機制
計畫編號:103-2314-B-195-001-MY3
執行期限:103/08/01~106/07/31

18.衛生福利部委託研究計畫-主持人

醫用電腦斷層掃瞄儀輻射暴露品質指標確保計畫

計畫編號:M03A2025    

執行期限:103/01/01~103/12/20

19.科技部103-106年一般型研究計畫(個別型)-主持人

發展左心房三維型態地圖導引及量化法於心血管疾病診斷及電腦斷層導引導管射頻燒灼

計畫編號:103-2314-B-010-005-MY3

執行期限:103/08/01~106/07/31

20.科技部103-106年一般型研究計畫(個別型)-共同主持人

心臟電腦斷層評估心室分區裝置於心室重建的機制

計畫編號:103-2314-B-195-001-MY3

執行期限:103/08/01~106/07/31

21.(104年)原子能合作代辦研究計畫(個別型) -主持人

評估心導管診療期間醫療曝露與職業曝露劑量並研擬最適化策略

計畫編號:104-NU-E-010-005-NU

執行期限:104/01/01~104/12/31

22. (104年)產學合作計畫-主持人

行動通訊電磁波地方宣導計畫

業界名稱:漢肯事業有限公司         

執行期限:104/08/06~104/11/30

23. (105年)原子能合作代辦研究計畫(個別型) -主持人

個人化核子醫學體內劑量評估—釔90影像實證研究

計畫編號:MOST 105-NU-E-010-002-NU;     

執行期限:105/01/01~105/12/31

24. (105年)原子能合作代辦研究計畫(個別型) -共同主持人

核醫用全身電腦斷層輻射劑量之風險評估

計畫編號:MOST 105-2623-E-075-002-NU;     

執行期限:105/01/01~105/12/31

25. (105年) 國立陽明大學暨亞東紀念醫院合作研究計畫-主持人

運動神經傳導疾病之診斷:前瞻性99mTc-TRODAT-1智慧分析軟體的開發

計畫編號:105FN04;     

執行期限:105/01/01~105/12/31

26. (105年)國立陽明大學生醫與醫材轉譯加值人才培訓計畫(SPARK)-主持人

嶄新的左心房壁地圖系統:壁厚視覺化且影像導引定位功能兼具

計畫編號:105A-002     

執行期限:105/08/01~106/07/31

27.(105年-108年)行政院原子能委員會委託研究計畫-共同主持人
北部地區輻射災害檢驗分析實驗室建置案
計畫編號:AEC10506020L
執行期限:105/08/11~108/12/31

28.(106年) 國立陽明大學暨亞東紀念醫院合作研究計畫-主持人
新式螺旋斷層治療儀設備治療食道癌:使用特有扇形完全阻擋以達劑量最佳化
計畫編號:106DN02                       
執行期限:106/01/01~106/12/31

29.(106年)原子能合作代辦研究計畫(個別型) -主持人
醫療輻射曝露劑量監控整合紀錄之研究
計畫編號:MOST 106-NU-E-010-002-NU    
執行期限:106/01/01~106/12/31

30.(106年)原子能合作代辦研究計畫(個別型) -共同主持人
低劑量策略與核醫影像品質最佳化研究
計畫編號:MOST 106-2623-E-075-002-NU   
執行期限:106/01/01~106/12/31

31.(104年-109年)教育部協助大學院校產學合作培育研發菁英計畫-指導教授
合作廠商:現代儀器股份有限公司         指導學生:林冠亨
執行期限:104/08/01~109/07/31

32.(104年-108年)教育部協助大學院校產學合作培育研發菁英計畫-指導教授
合作廠商:祐強醫療儀器有限公司         指導學生:陳冠名
執行期限:104/08/01~108/07/31

 

研究成果


這是一段多樣(Versatility)與實用(Applicability)兼具的漫長研究之旅,主持人自1999年起發表的SCI論文共計76篇,其中以第一作者或通訊作者身份所發表之論文篇數共計43篇,其他共同作者之論文共計33篇。另一方面,亦與國內各醫學中心密切合作,以激發創新技術並申請專利,期望能為放射醫療帶來更實質的產學人才培育與產學合作之發展。
 
I. 專利相關
   發明專利
      1. (台灣)定量分析核子醫學腦部影像的系統及方法
         (美國)System and Method for Quantitative Analysis of Nuclear Medicine Brain
               Imaging
         (中國)定量分析核子医学脑部影像的系统及方法
         發明人:吳東信、楊邦宏、李致賢、官郁翔
         專利權人:國立陽明大學
      2. (台灣)心臟醫學影像單一腔室地圖化系統及方法
         (美國)System and Method of Mapping Medical Image of Single Heart Chamber
         發明人:吳東信、孫靜儀、洪崇烈、惲純和
         專利權人:國立陽明大學
         計畫編號:MOST 103-2314-B-010-005-MY3

II. 放射診斷相關

1.  C.H. Yun, C.T. Longenecker, H.-R. Chang, Greta S.P. Mok, J.Y. Sun, C.C. Liu, J.Y. Kuo, C.L. Hung, T.H. Wu*(corresponding), H.I. Yeh, F.S. Yang, Jason J.S. Lee, Charles J.Y. Hou, R.C. Cury, H.G. Bezerra. The Association among Peri-Aortic Root Adipose Tissue, Metabolic derangements and Burden of Atherosclerosis in Asymptomatic Population. Journal of Cardiovascular Computed Tomography. Oct. 2016;10:44-51. (SCI; Category: radiology, nuclear medicine & medical imaging; IF: 2.472, Ranking: 42/124)

2.  C.H. Yun, J.T. Tsai, J.P. Tsai, Greta S.P. Mok, J.Y. Sun, C.L. Hung, T.H. Wu* (corresponding), F.S. Yang, Jason, J.S. Lee, R.C. Cury, H.G. Bezerra, Qualitative and Semi-quantitative evaluation of myocardium perfusion with 3T stress cardiac MRI, BMC Cardiovascular Disorders, 2015. 15:164 (SCI; Category: Cardiac & Cardiovascular systems; IF: 1.916; Ranking: 72/124)

3.  C.H. Yun, C.T. Longenecker, H.-R. Chang, Greta S.P. Mok, J.Y. Sun, C.C. Liu, J.Y. Kuo, C.L. Hung, T.H. Wu*(corresponding), H.I. Yeh, F.S. Yang, Jason J.S. Lee, Charles J.Y. Hou, R.C. Cury, H.G. Bezerra. Quantification of Peri-aortic root fat from non-contrast ECG-gated cardiac computed tomography. Data in Brief. Dec. 2015; 5:995-998. (SNIP: 0.111; SJR: 0.223)

4.  C.J. Lin, Greta S. P. Mok, M.F. Tsai, W.T. Tsai, B.H. Yang, C.Y. Tu*, T.H. Wu*(corresponding). National Survey of Radiation Dose and Image Quality in Adult CT Head Scans in Taiwan. June 30, 2015. PLoS ONE 10(6): e0131243. (SCI; Category: Multidisciplinary Sciences; Impact factor:3.057; Ranking: 11/63)

5.  T.H. Wu, S.C. Hung, J.Y. Sun, C.J. Lin, C.H. Lin, C.F. Chiu, M.J. Liu, Michael M.H. Teng, W.Y. Guo, C.Y. Chang, How far can the radiation dose be lowered in head CT with iterative reconstruction? Analysis of imaging quality and diagnostic accuracy, European Radiology, 04 May 2013;23(9):2612-2621. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; IF: 3.64; Ranking: 18/124)

6.  T.H. Wu, C.J. Lin, Y.H. Lin, W.C. Huang, W.Y. Guo, T.C. Huang, Quantitative analysis of digital subtraction angiography using optical flow method on occlusive cerebrovascular disease. Computer Methods and Programs in Biomedicine. Sep 2013;111(3):693-700. (SCI; Category: Computer Science, Theory & Methods; Impact factor:1.862; Ranking: 16/105)

7.  Y.W. Lee, C.C. Yang, S.P. Mok, W.Y. Law, C.T. Su, T.H. Wu*(corresponding), Prospective vs Retrospective ECG-Gated 256-slice CT Angiography to Assess Coronary Artery Bypass Grafts-Comparison of Image Quality and Radiation Dose. 2012; PLoS ONE 7(11): e49212. (SCI; Category: Multidisciplinary Sciences; Impact factor:3.057; Ranking: 11/63)

8.  Y.W. Lee, C.C. Yang, S.P. Mok and T.H. Wu*(corresponding), Infant Cardiac CT Angiography with 64-slice and 256-slice CT: Comparison of Radiation Dose and Image Quality Using a Pediatric Phantom. 2012; PLoS ONE 7(11): e49609. (SCI; Category: Multidisciplinary Sciences; Impact factor:3.057; Ranking: 11/63)

9.  J. Wu, C.T. Shih, S.J. Chang, T.C. Huang, J.Y. Sun, T.H. Wu*(corresponding), Metal artifact reduction algorithm based on model images and spatial information. Nuclear Instruments and Methods in Physics Research A Oct 2011;652:602-605. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

10. J. Wu, C.T. Shih, S.J. Chang, T.C. Huang, C.L. Chen, T.H. Wu* (corresponding), Evaluation of the impact of metal artifacts in CT-based attenuation correction of positron emission tomography scans. Nuclear Instruments and Methods in Physics Research A Aug 2011;648:S142-S145. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

11. L.K. Chen, S.M. Hsu, S.P. Mok, W.Y. Law, K.M. Lu, C.C. Yang*, T.H. Wu* (corresponding), 256-slice CT coronary angiography in atrial fibrillation: The impact of mean heart rate and heart rate variability on image quality. Nuclear Instruments and Methods in Physics Research A Aug 2011;648:S153-S157. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

12. G.S. Mok, C.C. Yang, L.K. Chen, K.M. Lu, W.Y. Law, and T.H. Wu* (corresponding), Optimal systolic and diastolic image reconstruction windows for coronary 256-slice CT angiography. Academic radiology Nov 2010;17: 1386-93. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:1.966; Ranking: 57/124)

13. W.Y. Guo, J.S. Lee, M.H. Lin, C.C. Yang, C.L. Chen, Y.H. Huang, Y.S. Tyan and T.H. Wu*(corresponding), Merging Molecular and Anatomic Information: A Feasibility Study on Rodents Using microPET and MRI. Nuclear Medicine Communications Oct 2007;28:804-812. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:1.453; Ranking: 87/124)

14. T.H. Wu, J.K. Wang, J.S. Lee, R.S. Liu and W.Y. Guo*, An Imaging Co-Registration System via Novel Non-Invasive and Non-Radioactive External Markers. European Journal of Nuclear Medicine and Molecular Imaging Jan 2003;30:812-818. (SCI; Category: Radiology; Impact factor:5.537; Ranking: 6/124)

15. C.H. Yang, T.H. Wu, C.J. Lin, Y.Y. Chiou, Y.C. Chen, M.H. Sheu, W.Y. Guo, C.F. Chiu. Knowledge-based iterative model reconstruction technique in computed tomography of lumbar spine lowers radiation dose and improves tissue differentiation for patients with lower back pain. European Journal of Radiology. Oct. 2016;85(10):1757-1764. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; IF: 2.593, Ranking: 36/124)

16. P.C. Chi, S.C. Chang, C.H. Yun, J.Y. Kuo, C.L. Hung, C.J.Y. Hou, C.Y. Liu, F.S. Yang, T.H. Wu, H.G. Bezerra, H.I. Yeh. The Associations between Various Ectopic Visceral Adiposity and Body Surface Electrocardiographic Alterations: Potential Differences between Local and Remote Systemic Effects. PLoS One. Jul. 2016;11(7):e0158300. (SCI; Category: Multidisciplinary Sciences; Impact factor:3.057; Ranking: 11/63)

17. S.T. Hung, C.H. Yun, T.H. Wu, F.S. Yang, J.Y. Kuo, C.L. Hung, C.J.Y. Hou, S.C. Chang, A. Fares, L.D. Nshisso, R.C. Cury, H.I. Yeh, H.G. Bezerra. Characteristic Features on Morphologic and Topographic Findings of Pulmonary Vein Orifices in Transition from Diastolic Dysfunction to Heart Failure: A Computerized Tomography Study. Journal of Cardiac Failure. April 2016;22(4):316-320. (SCI; Category: Cardiac & Cardiovascular Systems; Impact factor: 3.259; Ranking: 40/124)

18. Y.H. Lai, C.H. Yun, C.H. Su, F.S. Yang, H.I. Yeh, Charles J.Y. Hou, T.H. Wu, R.C Cury, H.G Bezerra, and C.L. Hung. Excessive interatrial adiposity is associated with left atrial remodeling, augmented contractile performance in asymptomatic population. Echo Res Pract. January 2016; 3(1):5-15. New journal (2015)

19. Y.H. Lai, Charles J.Y. Hou, C.H. Yun, K.T. Sung, J.Y. Kuo, T.H. Wu, F.S. Yang, H.I. Yeh, C.L. Hung, T.C. Hung , H.G. Bezerra. The association among MDCT-derived three-dimensional visceral adiposities on cardiac diastology and dyssynchrony in asymptomatic population. BMC Cardiovasc Disord. 2015 Oct; 15(1):142. (SCI; Category: Cardiac & Cardiovascular Systems; IF: 1.878, Ranking: 68/123)

20. F.S. Yang, C.H. Yun, T.H. Wu, Y.C. Hsieh, H.G. Bezerra, C.C. Liu, Y.J. Wu, J.Y. Kuo, C.L. Hung, Charles J.Y. Hou, H.I. Yeh, Jason J.S. Lee, B.E. Bulwer and R.C. Cury. High pericardial and peri-aortic adipose tissue burden in pre-diabetic and diabetic subjects. BMC Cardiovascular Disorders. November 2013;13:98. (SCI; Category: Cardiac & Cardiovascular systems; IF: 1.916; Ranking: 72/124)

21. C.H. Yun, Hiram G. Bezerra, T.H. Wu, F.S. Yang, C.C. Liu, Y.J. Wu, J.Y. Kuo, C.L. Hung, Jason J.S. Lee, Charles J.Y. Hou, H.I Yeh, Chris T. Longenecker, Ricardo C. Cury, The Normal Limits, Subclinical Significance, Related Metabolic Derangements and Distinct Biological Effects of Body Site-Specific Adiposity in Relatively Healthy Population. PLoS ONE, 19 April 2013, 8(4): e61997. (SCI; Category: Multidisciplinary Sciences; Impact factor:3.057; Ranking: 11/63)

22. T.C. Huang, T.H. Wu, Y.H. Lin, W.Y. Guo, W.C. Huang, C.J. Lin, Quantitative Flow Measurement by Digital Subtraction Angiography in Cerebral Carotid Stenosis Using Optical Flow Method. Journal of X-Ray Science and Technology, May 2013;21(2):227-235. (SCI; Category: Instruments & Instrumentation; Impact factor: 1.111; Ranking: 36/56)

23. C.J. Lin, T.H. Wu, C.H. Lin, S.C. Hung, C.F. Chiu, M.-J. Liu, M.M.H. Teng, F.C. Chang, W.Y. Guo, and C.Y. Chang. Can Iterative Reconstruction Improve Imaging Quality for Lower Radiation CT Perfusion? Initial Experience. AJNR Am. J. Neuroradiol. Aug 2013;34(8)1516-1521. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; IF: 3.124; Ranking: 24/124)

24. J. Wu, T.H. Wu, R. P. Han, S.J. Chang, C.T. Shih, J.Y. Sun, S.M. Hsu*, Comparison of the commercial color LCD and the medical monochrome LCD using randomized object test patterns. PLoS ONE May 2012; 7(5): e37769. (SCI; Category: Multidisciplinary Sciences; Impact factor:3.057; Ranking: 11/63)

25. T.C. Huang, T.H. Wu, C.J. Lin, S.P. Mok, W.Y. Guo*, Peri-therapeutic quantitative flow analysis of arteriovenous malformation on digital subtraction angiography. Journal of vascular surgery Sep 2012; 56(3):812-815 (SCI; Category: Surgery; Impact factor:3.454; Ranking: 21/199)

26. W.L. Hsu, T.H. Wu, S.M. Hsu, C.L. Chen, J.S. Lee*, Y.H. Huang*, An integrated multimodality image-guided robot system for small-animal imaging research. Nuclear Instruments and Methods in Physics Research A Oct 2011;652:763-766. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

27. T.C. Shih, G. Zhang, C.C. Wu, H.D. Hsiao, T.H. Wu, K.P. Lin, T.C. Huang*, Hemodynamic analysis of capillary in finger nail-fold using computational fluid dynamics and image estimation. Microvascular Research Jan 2011;81:68-72. (SCI; Category: Peripheral Vascular Disease; Impact factor: 2.3; Ranking: 39/63)

28. W.C. Lin, C.C. Wu, G. Zhang, T.H. Wu, Y.H. Lin, T.C. Huang*, R.S. Liu, K.P. Lin, An approach to automatic blood vessel image registration of microcirculation for blood flow analysis on nude mice. Computer methods in biomechanics and biomedical engineering Nov 2011;14(4):319-330. (SCI; Category: Computer Science, Interdisciplinary Applications; Impact factor: 1.850; Ranking: 39/104)

29. C.L. Chen, T. H. Wu, M.C. Cheng, Y.H. Huang, C.Y. Sheu, J.C. Hsiehc, J.S. Lee, Prospective demonstration of brain plasticity after intensive abacus-based mental calculation training: an fMRI study. Nuclear Instruments and Methods in Physics Research Section A Dec 2006;569:567-571. (SCI; Category: Nuclear Science & Technology; Impact factor:1.207; Ranking: 12/35)

30. Y. H. Huang, T. H. Wu, M. H. Lin, C. C. Yang, W.Y. Guo,c, Z.J. Wang, C.L. Chen, J. S. Lee*, An automated robot arm system for small animal tissue biopsy under dual-image modality. Nuclear Instruments and Methods in Physics Research Section A Dec 2006;569:230-234. (SCI; Category: Nuclear Science & Technology; Impact factor:1.207; Ranking: 12/35)

31. C.C. Yang, T.H. Wu, M.H. Lin, Y.H. Huang, W.Y. Guo, C.L.Chen, T.C. Wang, W.H. Yin, J.S. Lee*, Multimodality imaging combination in small animal mode via point-based registration. Nuclear Instruments and Methods in Physics Research Section A Dec 2006;569:240-244. (SCI; Category: Nuclear Science & Technology; Impact factor:1.207; Ranking: 12/35)

 

 

III. 核子醫學相關

1.  T.H. Wu, K.M. Lu, N.Y. Wu, S.J. Wang, S.P. Mok, B.H. Yang and C.C. Yang. The feasibility of low-dose CT protocols for coronary artery calcium scoring and PET attenuation correction in cardiac PET/CT. Nuclear Medicine Communications April 2015;36(4):376-385. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:1.453; Ranking: 87/124)

2.  C.C. Yang, J.A. Yu, B.H. Yang, T.H. Wu*(corresponding), Optimization of the scan protocols for CT-based material extraction in small animal PET/CT studies, Nuclear Instruments and Methods in Physics Research A, December 2013;731:299-304. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

3.  T.H. Wu, J.A. Yu, and C.C. Yang,, An Investigation of PET Scan Parameters for Lesion Detection With GE VISTA Small-Animal Scanner Using Monte Carlo Simulation and Multivariate Analysis, IEEE Transactions on nuclear science, April 2013;60(2):774-782. (SCI; Category: Nuclear Science & Technology; Impact factor:1.198; Ranking: 10/32)

4.  S.P. Mok, Y.Y. Wu, K.M. Lu, J. Wu*, L.K. Chen*, T.H. Wu*(corresponding), Evaluation of the Screening Power of Cognitive Abilities Screening Instrument for Probable Alzheimer's Disease Using Voxel-Based Morphometry. Clinical Imaging Jan 2012;36:46-53. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:0.966; Ranking: 109/124)

5.  T.C. Huang, S.P. Mok, S.J. Wang, T.H. Wu*(corresponding), G. Zhang, Attenuation correction of PET images with interpolated average CT for thoracic tumors. Physic in medical and biology Mar 2011;56: 2559-2567. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:2.811; Ranking: 32/124)

6.  W.Y. Law, C.C. Yang, L.K. Chen, T.C. Huang, K.M. Lu, T.H. Wu* (corresponding) and S.P. Mok, Retrospective Gating vs. Prospective Triggering for Noninvasive Coronary Angiography: Assessment of Image Quality and Radiation Dose Using a 256-Slice CT Scanner with 270 ms Gantry Rotation. Academic Radiology Jan 2011;18:31-39. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:1.966; Ranking: 57/124)

7.  T.H. Wu, N.Y. Wu, S.J. Wang, J. Wu, S.P. Mok, C.C. Yang*, T.C. Huang*, Strategies to reduce radiation dose in cardiac PET/CT. Nuclear Instruments and Methods in Physics Research A Aug 2011;648:S158-S162. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

8.  T.C. Huang, G. Zhang, C.H. Chen, B.H. Yang, N.Y. Wu, S.J. Wang*, T.H. Wu*(corresponding), Attenuation correction of emission PET images with average CT: Interpolation from breath-hold CT. Nuclear Instruments and Methods in Physics Research A May 2011;633:S156-S158. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

9.  T.H. Wu, G. Zhang, S.J. Wang, C.H. Chen, B.H. Yang, N.Y. Wu, and T.C. Huang*, Low-dose interpolated average CT for attenuation correction in cardiac PET/CT. Nuclear Instruments and Methods in Physics Research A Jul 2010;619:361- 364. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

10. S.J. Wang, B.H Yang, C.J Tsai, C.C. Yang, J.S. Lee, and T.H. Wu* (corresponding), Ultra low-dose CT attenuation correction in PET SPM. Nuclear Instruments and Methods in Physics Research A Jul 2010;619: 397-400. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

11. T.H. Wu, C.L. Chen, Y.H. Huang, J.C. Hsieh and J.S. Lee*, Effects of Long-Term Practice and Task Complexity on Brain Activities When Performing Abacus-based Mental Calculations: a PET study. European Journal of Nuclear Medicine and Molecular Imaging Mar 2009;36:436-445. (SCI; Category: Radiology; Impact factor:5.537; Ranking: 6/124)

12. T.H. Wu, C.H. Liang, J.K. Wu, C.Y. Lien, B.H. Yang, Y.H. Huang and J.S. Lee*, Integration of PET-CT and cone-beam CT for image-guided radiotherapy with high image quality and registration accuracy. Journal of Instrumentation Jul 2009; JINST 4 P07006. (SCI; Category: Instruments & Instrumentation; Impact factor:1.31; Ranking: 28/56)

13. T.H. Wu, T.C. Chu, Y.H. Huang, L.K. Chen, S.P. Mok, J.K. Lee, Y.S. Tyan and J.S. Lee*, A positron emission tomography/computed tomography (PET/CT) acquisition protocol for CT radiation dose optimization. Nuclear Medicine Communications Apr 2005;26:323-330. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:1.453; Ranking: 87/124)

14. T.H. Wu, Y.H. Huang, J.S. Lee, S.Y. Wang, S.C. Wang, C.T. Su, L.K. Chen and T.C. Chu*, Radiation exposure during transmission measurements: comparison between CT- and germanium-based techniques with a current PET scanner. European Journal of Nuclear Medicine and Molecular Imaging Jan 2004;31:38-43. (SCI; Category: Radiology; Impact factor:5.537; Ranking: 6/124)

15. T.H. Wu, R.S. Liu, S.L. Dong, Y.W. Chung, K.L. Chou, J.S. Lee*, Dynamic Evaluation of Absorbed Dose to The Bladder Wall with a Balloon-Bladder Phantom During a Study Using [18F]Fluorodeoxyglucose Positron Emission Imaging. Nuclear Medicine Communications Aug 2002;23:749-757. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:1.453; Ranking: 87/124)

16. T.H. Wu, R.S. Liu, N.S. Chong, C.S. Tsai and J. S. Lee*, Evaluation of Equivalent Dose to Working Staff with Oxygen-15-Water in Positron Emission Tomographic Studies. Applied Radiation and Isotopes, Sep 2000;53:463-468. (SCI; Category: Nuclear Science & Technology; Impact factor:1.136; Ranking: 14/32)

17. T.H. Wu, R.S. Liu, Y.D. Lin, K.L. Chou, N.S. Chong and J.S. Lee*, Evaluation of The Dose to The Bladder Wall Using A Dynamic Balloon-Bladder Phantom and TLD Measurements in PET [F-18]FDG Studies. Nuclear Medicine Communications, Dec 1999;20:1153-1159. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:1.453; Ranking: 87/124)

18. G.S. Mok, C.Y. Ho, B.H. Yang, T.H. Wu. Interpolated average CT for cardiac PET/CT attenuation correction. Journal of Nuclear Cardiology. October 2016; 23(5):1072–1079. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; IF: 2.929, Ranking: 27/124)

19. C.Y. Ho, T.H. Wu, G.S. Mok. Interpolated average CT for PET attenuation correction in different lesion characteristics. Nuclear Medicine Communications. Mar. 2016;37(3):297-306. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:1.453; Ranking: 87/124)

20. J.P. Tsai, C.H. Yun, T.H. Wu, C.H. Yen, C.J. Hou, J.Y. Kuo, C.L. Hung. A meta-analysis comparing SPECT with PET for the assessment of myocardial viability in patients with coronary artery disease. Nuclear Medicine Communications. September 2014; 35:947-954. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:1.453; Ranking: 87/124)

21. T. Sun, T.H. Wu, S.J. Wang, B.H. Yang, N.Y. Wu and Greta, S.P. Mok. Low dose interpolated average CT for thoracic PET/CT attenuation correction using active breathing controller (ABC). Medical physics. October 2013;40(10): 102507. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:2.496; Ranking: 41/124)

22. W.L. Hsu*, C.L.Chen, T.C. Wang, T.H. Wu, D.W. Liu, Jason JS Lee, Feasibility study of small animal imaging using clinical PET/CT scanner. Nuclear Instruments and Methods in Physics Research Section A Feb 2007;571:457-460. (SCI; Category: Nuclear Science & Technology; Impact factor:1.207; Ranking: 12/35)

23. Y.H. Huang, T.H. Wu, C.T. Su and J.S. Lee*, Absorbed dose evaluation to patients undergoing PET/CT and conventional CT examinations. Radiation Physics and Chemistry Nov 2004;71:985-986. (SCI; Category: Nuclear Science & Technology; Impact factor:1.207; Ranking: 7/32)    

 

 

IV. 放射治療與輻射劑量相關

1.  C.H. Chang, S.P. Mok, P.W. Shueng, H.P. Yeh, A.C. Shiau, H.J. Tien, C.T Lin, T.H. Wu*(corresponding), Fan-shaped complete block on helical tomotherapy for esophageal cancer: a phantom study. BioMed Research International. Volume 2015, Article ID 959504, 6 pages. http://dx.doi.org/10.1155/2015/959504 (SCI; Category: Medicine, Research & Experimental; Impact factor: 2.134; Ranking: 72/124)

2.  W.F. Chu, C.J. Lin, W.S. Chen, S.C. Hung, C.F. Chiu, T.H. Wu*(corresponding), and W.Y. Guo, Radiation Doses of Cerebral Blood Volume Measurements Using C-Arm CT: A Phantom Study. AJNR American Journal of Neuroradiology. Jun 2014;35(6):1073-1077. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; IF: 3.124; Ranking: 24/124)

3.  C.C. Yang, S.P. Mok, W.Y. Law, S.M. Hsu*, T.H. Wu* (corresponding) and L.K. Chen*, Potential Dose Reduction of Optimal ECG-controlled Tube Current Modulation for 256-slice CT Coronary Angiography. Academic Radiology 2011; 18:731–737. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:1.966; Ranking: 57/124)

4.  C.C. Yang, J. Wu, C.C. Chen, Y.C. Liu, C.F. Hung and T.H. Wu*(corresponding), Radiation dose in 320-detector-row CT coronary angiography: prospective ECG triggering combined with multi-segment reconstruction. Radiation Measurements Dec 2011;46:2060-2064. (SCI; Category: Nuclear Science & Technology; Impact factor:1.071; Ranking: 16/32)

5.  H.L. Chen, Y.H. Huang, T.H. Wu*(corresponding), S.Y. Wang, J.S. Lee*, Dose distribution and mapping with 3D imaging presentation in intraoral and panoramic examinations. Nuclear Instruments and Methods in Physics Research A Oct 2011;652:759-762. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

6.  C.J. Tsai, J.S. Lee, L.K. Chen, S.P. Mok, S.M. Hsu*, T.H. Wu* (corresponding), Evaluation of radiation dose of triple rule-out coronary angiography protocols with different scan length using 256-slice CT. Nuclear Instruments and Methods in Physics Research A Oct 2011;652:771-774. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

7.  T.H. Wu, C.J. Tsai, G. Zhang, C.Y. Yu, J.A. Liang, J. Wu, J.S. Lee, Y.J. Ho, T.C. Huang*, A novel application of normoxic polymer gel dosimeters for near real-time dose measurement using cone-beam computed tomography. Nuclear Instruments and Methods in Physics Research A May 2011;633:S279-S281. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

8.  T.C. Huang, J.A. Liang, T. Dilling, T.H. Wu*(corresponding), and G. Zhang, Four-dimensional dosimetry validation and study in lung radiotherapy using deformable image registration and Monte Carlo techniques. Radiation Oncology May 2010;5:45. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:2.466; Ranking: 43/124)

9.  K.M. Huang, T.C. Huang, C.J. Tsai, K.M. Lu, L.K. Chen*, T.H. Wu* (corresponding), High-resolution gel dosimetry using flat-panel detector cone-beam computed tomography: preliminary study. Applied Radiation and Isotopes Apr-May 2010;68:607-609. (SCI; Category: Nuclear Science & Technology; Impact factor:1.136; Ranking: 14/32)

10. M.H. Lin, T.C. Huang, M.J. Kao, J. Wu, C.L. Chen, and T.H. Wu* (corresponding), Three-dimensional dosimetry in brachytherapy: A MAGAT study. Applied Radiation and Isotopes July-August 2009;67:1432-1437. (SCI; Category: Nuclear Science & Technology; Impact factor:1.136; Ranking: 14/32)

11. J.S. Lee, C.J. Tsai, M.K. Lo, Y.H. Huang, C.C. Chen, J. Wu, Y.S. Tyan and  T.H. Wu*(corresponding), Investigation of dose characteristics in three-dimensional MAGAT-type polymer gel dosimetry with MSE MR imaging. Nuclear Instruments and Methods in Physics Research B May 2008;266: 2199-2202. (SCI; Category: Nuclear Science & Technology; Impact factor:1.389; Ranking: 5/32)

12. T.H. Wu, J.S. Lee, H.M Wu, W.F. Chu, W.Y. Guo*, Evaluating Geometric Accuracy of Multi-platform Stereotactic Neuroimaging in Radiosurgery. Stereotactic and Functional Neurosurgery Oct 2002;78:39-48. (SCI; Category: Surgery; Impact factor:1.691; Ranking: 87/199)

13. C.C. Yang, S.H. Liu, Greta S. P. Mok, and T.H. Wu. Evaluation of radiation dose and image quality of CT scan for whole-body pediatric PET/CT: A phantom study. Medical Physics. September 2014;41(9):092505. (SCI; Category: Radiology, Nuclear Medicine & Medical Imaging; Impact factor:2.496; Ranking: 41/124)

14. F.Y. Hsu, W.F. Lee, C.J. Tung, J.S. Lee, T.H. Wu, S.M. Hsu, H.T. Su, T.R. Chen. Ambient and personal dose assessment of a container inspection site using a mobile X-ray system. Applied Radiation and Isotopes. Mar 2012;70:456–461. (SCI; Category: Nuclear Science & Technology; Impact factor:1.136; Ranking: 14/32)

15. C.J. Tsai, L.K. Chen, S.P. Mok, T.H. Wu and J.S. Lee*, Dose reduction in 256-slice triple rule-out CT angiography. Radiation Measurements Dec 2011;46:2065-2068. (SCI; Category: Nuclear Science & Technology; Impact factor:1.071; Ranking: 16/32)

16. K.Y. Chang, T.Y. Shih, B.T. Hsieh, S.J. Chang, Y.L. Liu, T.H. Wu, J. Wu*, Investigation of the dose characteristics of an n-NIPAM gel dosimeter with computed tomography. Nuclear Instruments and Methods in Physics Research A Oct 2011;652:775-778. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

17. L.K. Chen, T.H. Wu, C.C. Yang, C.J. Tsai, J.S. Lee*, Radiation dose to patients and image quality evaluation from coronary 256-slice computed tomographic angiography. Nuclear Instruments and Methods in Physics Research A Jul 2010;619:368-371. (SCI; Category: Nuclear Science & Technology; Impact factor:1.2; Ranking: 9/32)

18. C.H.Cheng, C.H. Liang, J.K. Wu, K.M. Huang, T.H. Wu, C.J. Tsai, C.L. Chen and J.S. Lee*, Evaluation of radiation dose and positioning accuracy on X-ray volume imaging system for image-guided radiotherapy. Nuclear Instruments and Methods in Physics Research B May 2008;266: 2203-2206. (SCI; Category: Nuclear Science & Technology; Impact factor:1.389; Ranking: 5/32)

19. S.L Dong, T.C. Chu, G.Y. Lan, T.H. Wu, Y.C. Lin, J.S. Lee*, Characterization of High-Sensitivity Metal Oxide Semiconductor Field Effect Transistor Dosimeters System and LiF:Mg,Cu,P Thermoluminescence Dosimeters for Use in Diagnostic Radiology. Applied Radiation and Isotopes Dec 2002;57:883-891. (SCI; Category: Nuclear Science & Technology; Impact factor:1.136; Ranking: 14/32)